Peptides are chains of amino acids, typically containing between 2 and 50 amino acids. These smaller forms of proteins play various roles in the body, acting as neurotransmitters, hormones, or influencing the body’s response to activities and diet. Due to their smaller size, peptides are more readily processed by the body and can offer numerous benefits. They can be derived from both animal and plant protein sources.

There are currently at least 100 peptides in use in the medical field across the United States, Japan, and parts of Europe, according to the FDA. Some common peptides used in various treatments include:

• CJC 1295: Used for treating certain diseases and muscle disorders, and for improving strength, supporting weight loss, and increasing lean muscle mass.
• IGF-1 LR3: Promotes the growth of new muscles and cells through hyperplasia.
• Sermorelin: Helps the body produce its own growth hormones, often used for children with growth hormone deficiencies.
• Ipamorelin: A growth hormone peptide that improves energy levels, reduces body fat, and speeds up workout recovery.
• BPC 157: Supports tendon and bone injury recovery and is popular among athletes.

Most forms of peptide therapy are generally safe, with many peptides cleared by the FDA for medical use and clinical trials. To ensure safety and effectiveness, it is important to receive treatments from a reliable practitioner. Peptides can be natural or synthetic, and well-designed synthetic peptides are safe when sourced from reputable sellers. Some minimal side effects may include:

• Increased hunger or thirst
• Dry mouth
• Itching at the injection site
• Some drowsiness

Peptide therapy typically involves injecting peptides into the skin, allowing them to enter the bloodstream quickly without needing to be broken down by other bodily systems. Some peptides are also available in oral capsules, topical lotions or creams, and nasal sprays. For more reliable results, injections are often preferred, administered on a schedule determined by your healthcare provider.

Peptide therapy is not an instant cure-all but a supportive treatment that can aid in various issues. Some peptides may take several weeks or months to produce noticeable effects, while others may result in immediate changes in energy levels or workout recovery.

To measure the effectiveness of peptide therapy, use measurable metrics such as annual follow-up labs and body composition scanners like Dexa Scan. Sleep monitors like the Oura Ring, Apple Watch, Fitbit, or Go2Sleep can also provide useful data.

Yes, but some peptides should be cycled for optimal effects. BPC-157 and topical GHK-Cu can be used long term without cycling, while TA-1 can also be used long term. Sermorelin and TB-4 are best cycled, and PT-141 should be used intermittently rather than daily.

The recommended peptides have not been shown to increase cancer risk when used as directed. However, it is not advised to use Sermorelin or TB-4 if you have cancer, and Melanotan 1 should not be used if you have a history of melanoma.

Yes, peptides from a reliable and approved compounding pharmacy are stable at room temperature for up to 7 days. For travel, store them in a Yeti cup and keep them in a refrigerator at your destination.

Unless the bottle specifically states “inject before bed” or “inject 30 min before x activity” (e.g., PT-141), the time of day does not matter.

The following peptides are FDA approved: TA-1, TB4, Sermorelin, PT-141, BPC-157, and topical GHK-Cu. These peptides are manufactured specifically for you in an FDA-approved facility using FDA-approved ingredients.

While many peptides have a favorable safety profile, some users might experience side effects. These can vary depending on the specific peptide being used:

• Injection Site Reactions: Redness, swelling, or pain at the injection site can occur, especially for those new to injections.
• Nausea: Certain peptides, such as PT-141 or Melanotan 1, may cause nausea. This can be exacerbated by specific dietary programs like ProLon.
• Fatigue: Some individuals might feel tired or fatigued after peptide administration.
• Headaches: Headaches can be a common side effect, particularly when starting a new peptide regimen.
• Dizziness: Some peptides might cause dizziness or lightheadedness.

Different peptides can have unique side effects:

• TA-1 (Thymosin Alpha-1): Generally well-tolerated with no significant adverse reactions reported.
• BPC-157: Typically has a high safety profile with minimal side effects.
• GHK-Cu: This topical peptide is generally safe with rare occurrences of skin irritation.
• Sermorelin: Should not be used by individuals with cancer due to potential growth factor stimulation.
• TB-4 (Thymosin Beta-4): Not recommended for cancer patients as it may influence tumor growth.
• PT-141: Known for causing nausea and potential changes in blood pressure; should be used intermittently.

For long-term safety and effectiveness, some peptides should be cycled:

• BPC-157 and GHK-Cu: Can be used long term without cycling.
• Sermorelin and TB-4: Best used in cycles to prevent potential side effects.
• PT-141: Should be used intermittently rather than daily.